Study of immunobiological properties of avian adenovirus serotype 2-based vaccine against adenovirus infection
Abstract
The data on studying immunogenic activity of the inactivated vaccine produced on the basis of avian adenovirus isolate FAdV-2 are demonstrated in the paper. The dynamics of antibody accumulation in chicken blood is shown. The high resistance of immunized chicks to homologous virus (FAdV-2) infection and lack of protection against heterologous virus (FAdV-4) infection are also demonstrated.
About the Authors
A. A. Perepecha
FGBI "ARRIAH", Vladimir
Russian Federation
Russian Federation
S. V. Frolov
FGBI "ARRIAH", Vladimir
Russian Federation
Russian Federation
D. L. Dolgov
FGBI "ARRIAH", Vladimir
Russian Federation
Russian Federation
M. A. Volkova
FGBI "ARRIAH", Vladimir
Russian Federation
Russian Federation
D. A. Gleyzer
FGBI "ARRIAH", Vladimir
Russian Federation
Russian Federation
References
1. Волкова М.А., Ирза A.B., Бахчин И.В. Иммунный ответ цыплят на экспериментальное заражение изо-лятом аденовируса птиц FAdV2/1/2012//Тр. Федерального центра охраны здоровья животных. - Владимир, 2014. - Т. 12. - С. 121-132.
2. Волкова М.А., Ирза A.B., Лазарева С.П. Идентификация аденовируса птиц, выделенного в Российской Федерации от кур с признаками гепатита, с использованием ПЦР-РВ и ИФА//Тр. Федерального центра охраны здоровья животных. - Владимир, 2013. - Т. 11. - С. 34-42.
3. Deshmukh V.V.,Aziz A.,Gujar M.B. Humoral immune response in broilers against inclusion body hepatitis virus // Indian J. Animal Sciences. - 2000.-Vol. 70, № 4. - P. 340-342.
4. El-Attrache J., Villegas P. Genomic identification and characterization of avian adenoviruses associated with inclusion body hepatitis // Avian Dis. - 2001. - Vol. 45, № 4. - P. 780-787.
5. Genotyping of Canadian isolates o ffowl adenoviruses/D.Ojkic, E. Martin, J.Swinton [et a I.] //Avian Pathol. - 2008. - Vol. 37, № 1. - P. 95-100.
6. Hess M. Detection and differentiation of avian adenoviruses: A review/М. Hess// Avian Pathol. - 2000. - Vol. 29, №3, -P. 195-206.
7. Inclusion body hepatitis outbreak associated with fowl adenovirus type 8b in broilers /М. Zadravec [et a I.] // Acta Veterinaria. - 2013. - Vol. 63, № 1. - P. 101 -110.
8. Isolation of viruses from clinical outbreaks of inclusion body hepatitis / J.B. McFerran [et al.] // Avian Pathol. - 1976, -Vol. 5. - P. 315-324.
Review
For citations:
Perepecha A.A., Frolov S.V., Dolgov D.L., Volkova M.A., Gleyzer D.A. Study of immunobiological properties of avian adenovirus serotype 2-based vaccine against adenovirus infection. Veterinary Science Today. 2015;(2):35-37. (In Russ.)
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