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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">veterinary</journal-id><journal-title-group><journal-title xml:lang="ru">Ветеринария сегодня</journal-title><trans-title-group xml:lang="en"><trans-title>Veterinary Science Today</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-196X</issn><issn pub-type="epub">2658-6959</issn><publisher><publisher-name>"Veinard"</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">veterinary-192</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Изучение иммунобиологических свойств вакцины против аденовирусной инфекции, изготовленной на основе аденовируса птиц 2 серотипа</article-title><trans-title-group xml:lang="en"><trans-title>Study of immunobiological properties of avian adenovirus serotype 2-based vaccine against adenovirus infection</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Перепеча</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Perepecha</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">perepecha@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фролов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Frolov</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Долгов</surname><given-names>Д. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Dolgov</surname><given-names>D. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волкова</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Volkova</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Глейзер</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Gleyzer</surname><given-names>D. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «ВНИИЗЖ», г. Владимир</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FGBI "ARRIAH", Vladimir</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>02</day><month>04</month><year>2018</year></pub-date><volume>0</volume><issue>2</issue><fpage>35</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Перепеча А.А., Фролов С.В., Долгов Д.Л., Волкова М.А., Глейзер Д.А., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Перепеча А.А., Фролов С.В., Долгов Д.Л., Волкова М.А., Глейзер Д.А.</copyright-holder><copyright-holder xml:lang="en">Perepecha A.A., Frolov S.V., Dolgov D.L., Volkova M.A., Gleyzer D.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://veterinary.arriah.ru/jour/article/view/192">https://veterinary.arriah.ru/jour/article/view/192</self-uri><abstract><p>В работе представлены данные по изучению иммуногенной активности инактивированной вакцины, изготовленной на основе изолята аденовируса птиц FAdV-2. Показана динамика накопления антител в крови цыплят. Также продемонстрирована высокая устойчивость иммунизированных цыплят к заражению гомологичным вирусом (FAdV-2) и отсутствие такой защиты кзаражению гетерологичным вирусом (FAdV-4).</p></abstract><trans-abstract xml:lang="en"><p>The data on studying immunogenic activity of the inactivated vaccine produced on the basis of avian adenovirus isolate FAdV-2 are demonstrated in the paper. The dynamics of antibody accumulation in chicken blood is shown. The high resistance of immunized chicks to homologous virus (FAdV-2) infection and lack of protection against heterologous virus (FAdV-4) infection are also demonstrated.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>аденовирус птиц</kwd><kwd>инактивированная вакцина</kwd><kwd>антиген</kwd><kwd>специфические антитела</kwd><kwd>иммуногенность</kwd><kwd>avian adenovirus</kwd><kwd>inactivated vaccine</kwd><kwd>antigen</kwd><kwd>specific antibodies</kwd><kwd>immunogenicity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Волкова М.А., Ирза A.B., Бахчин И.В. Иммунный ответ цыплят на экспериментальное заражение изо-лятом аденовируса птиц FAdV2/1/2012//Тр. Федерального центра охраны здоровья животных. - Владимир, 2014. - Т. 12. - С. 121-132.</mixed-citation><mixed-citation xml:lang="en">Волкова М.А., Ирза A.B., Бахчин И.В. 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