Возможности метода капиллярного электрофореза при анализе готовых лекарственных средств антибактериального действия

В работе оценена возможность контроля качества готовых лекарственных средств методами капиллярного электрофореза. Выбраны оптимальные условия разделения и определения различных классов антибактериальных веществ: пенициллинов, фторхинолонов, нитрофуранов, сульфаниламидов, метронидазола и хлорамфеникола. Диапазон определяемых содержаний действующих компонентов составил 1-2500 мг/г для твердых образцов и 0,001 -0,50% для жидких препаратов.

готовые лекарственные средства, капиллярный зонный электрофорез, мицеллярная электрокинетическая хроматография, антибиотики, антибактериальные вещества, ready-to-use pharmaceuticals, capillary zone electrophoresis, micellar electrokinetic chromatography, antibiotics, antibacterial agents

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