Capabilities of capillary electrophoresis for analysis of ready-to-use pharmaceutical products with an antibacterial effect
Abstract
The capability to monitor quality of ready-to-use pharmaceuticals using capillary electrophoresis methods is evaluated in the paper. Optimal conditions for separation and determination of different classes of such antibacterial agents as penicillins, fluoroquinolones, nitrofurans, sulfanilamides, metronidazole and chloramphenicol are chosen. The range of content of active constituents is 1-2500 mg/g for solid samples and 0,001-0,50% for liquid preparations.
About the Authors
D. S. Bolshakov
FGBI "ARRIAH", Vladimir
Russian Federation
Russian Federation
V. G. Amelin
FGBI "ARRIAH", Vladimir
Russian Federation
Russian Federation
T. B. Nikeshina
FGBI "ARRIAH", Vladimir
Russian Federation
Russian Federation
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Review
For citations:
Bolshakov D.S., Amelin V.G., Nikeshina T.B. Capabilities of capillary electrophoresis for analysis of ready-to-use pharmaceutical products with an antibacterial effect. Veterinary Science Today. 2015;(1):29-36. (In Russ.)
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