Preview

Veterinary Science Today

Advanced search

Prospects of betulin application in broiler farming

https://doi.org/10.29326/2304-196X-2020-4-35-277-282

Abstract

It is an urgent task today to seek and implement nature-like technologies in broiler production and obtain biologically complete and safe poultry products, thus refusing from antibiotic use in feed. Feed additives based on natural components can be an effective tool for implementation of preventive and therapeutic veterinary measures. The paper presents research study results of application of betulin-based phytobiotics in broiler farming. The tests were carried out on Ross-308 cross-breed broiler chickens within the production cycle at one of the poultry farms of the Sverdlovsk Oblast. Birds of the experimental group received compound feed supplemented with dry betulin at 2.5 mg/kg of live weight from day 21 to day 35 of growing. The introduction of betulin-based feed additive into the diet contributed to increase in live weight gain and 7.6% pectoralis muscle output as compared with the control group. It was established that the phytobiotic consumption resulted in reduced deposition of subcutaneous and abdominal fat, higher biological value of meat by increasing the ash content, improved technological properties of meat due to increasing water-holding capacity of muscle fiber and intensity of formation and maturation of muscle fiber. Histological studies of pancreatic tissue samples from broiler chickens showed increase in the mass of islets of Langerhans and insulin-producing cell complexes. The pancreas was activated due to effects of the betulin-based feed additive. The results obtained indicate that the use of betulin in broiler production is a promising trend.

About the Authors

M. V. Novikova
Federal State Budgetary Scientific Institution “Ural Federal Agrarian Scientific Research Centre, Ural Branch of the Russian Academy of Sciences” (FSBSI UrFASRC UrB of RAS)
Russian Federation

Maria V. Novikova, Candidate of Science (Biology), Senior Researcher, Department for Commercial Poultry Breeding

Ekaterinburg



I. A. Lebedeva
Federal State Budgetary Scientific Institution “Ural Federal Agrarian Scientific Research Centre, Ural Branch of the Russian Academy of Sciences” (FSBSI UrFASRC UrB of RAS)
Russian Federation

Irina A. Lebedeva, Doctor of Science (Biology), Associate Professor, Leading Researcher, Department for Commercial Poultry Breeding

Ekaterinburg



L. I. Drozdova
Federal State Budgetary Scientific Institution “Ural Federal Agrarian Scientific Research Centre, Ural Branch of the Russian Academy of Sciences” (FSBSI UrFASRC UrB of RAS)
Russian Federation

Lyudmila I. Drozdova, Doctor of Science (Veterinary Medicine), Professor, Senior Researcher

Ekaterinburg



A. V. Byuler
Federal State Budgetary Scientific Institution “Ural Federal Agrarian Scientific Research Centre, Ural Branch of the Russian Academy of Sciences” (FSBSI UrFASRC UrB of RAS)
Russian Federation

Alexey V. Byuler, Candidate of Science (Chemistry), Senior Researcher, Department for Commercial Poultry Breeding

Ekaterinburg



References

1. Buhler A. V., Lebedeva I. A., Novikova M. V., Ignatyev V. E. Effects of emulsified betulin-based adaptogenic feed additive on the structure and chemical composition of broiler chicken liver [Vliyanie adaptogennoj kormovoj dobavki na osnove emul’girovannogo betulina na strukturu i himicheskij sostav pecheni cyplyat-brojlerov]. In: Modern trends of scientific support in the agro-industrial complex development: fundamental and applied research [Sovremennye tendencii nauchnogo obespecheniya v razvitii APK: fundamental’nye i prikladnye issledovaniya]: materials of a Scientific-practical (in-praesentia/in-absentia) Conference with International Participation. Omsk; 2017: 116–119. eLIBRARY ID: 30530530. (in Russian)

2. Zadorozhnaya M. V., Lysko S. B., Krasikov A. P. Effectiveness of betu lin in poultry. Veterinarnyj vrach. 2012; 5: 34–36. eLIBRARY ID: 18235683. (in Russian)

3. Lebedeva I. A., Buhler A. V., Novikova M. V. Stimulation of follicle maturation in the parent flock of hens. Reprod. Domest. Anim. 2019; 54 (S3): 116. eLIBRARY ID: 39566304.

4. Li X. D., Zhang Y. J., Han J. C. Betulin inhibits lung carcinoma proliferation through activation of AMPK signaling. Tumor Biol. 2014; 35 (11): 11153– 11158. DOI: 10.1007/s13277-014-2426-7.

5. Mikova N. M., Chesnokov N. V., Mazurova E. V., Pavlenko N. I., Ivanchenko N. M. Thermal transformation of betulin by alkaline activation. Russian Journal of Bioorganic Chemistry. 2016; 42 (7): 741–747. DOI: 10.1134/S1068162016070104.

6. Myz S. A., Shakhtshneider T. P., Mikhailenko M. A., Ogienko A. G., Bogdanova E. G., Ogienko A. A., et al. Ultrafine betulin formulation with biocompatible carriers exhibiting improved dissolution rate. Natural Product Communications. 2015; 10 (8): 1345–1347. DOI: 10.1177/1934578x1501000806.

7. Novikova M., Lebedeva I. Improvement of reproductive potential of chicken hens from parent broiler flock by means of the use of supplements based on triterpene spirits. Reprod. Domest. Anim. 2018; 53 (S2): 174. eLIBRARY ID: 35607552.

8. Pokorny J., Horka V., Sidova V., Urban M. Synthesis and characteri zation of new conjugates of betulin diacetate and bis (triphenysilyl) betulin with substituted triazoles. Monatsh. Chem. 2018; 149: 839–845. DOI: 10.1007/s00706-017-2113-7.

9. Pozharitskaya O. N., Karlina M. V., Shikov A. N., Kosman V. M., Makarov V. G., Casals E., Rosenholm J. M. Pharmacokinetics and tissue disposition of nano-system-entrapped betulin after endotracheal administration to rats. Eur. J. Drug Metab. Pharmacokinet. 2017; 42: 327–332. DOI: 10.1007/s13318-016-0340-7.

10. Shakhtshneider T. P., Mikhailenko M. A., Drebushchak V. A., Drebushchak T. N., Malyar Yu. N., Kuznetsova S. A. Effect of ball-milling on preparation of composites of betulin and betulin diacetate with polyethylene glycol. In: Fundamental Bases of Mechanochemical Technologies: The Book of Abstracts of the V International Conference. Novosibirsk; 2018: 153. eLIBRARY ID: 36711414.


Review

For citations:


Novikova M.V., Lebedeva I.A., Drozdova L.I., Byuler A.V. Prospects of betulin application in broiler farming. Veterinary Science Today. 2020;(4):277-282. https://doi.org/10.29326/2304-196X-2020-4-35-277-282

Views: 915


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2304-196X (Print)
ISSN 2658-6959 (Online)