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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">veterinary</journal-id><journal-title-group><journal-title xml:lang="ru">Ветеринария сегодня</journal-title><trans-title-group xml:lang="en"><trans-title>Veterinary Science Today</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-196X</issn><issn pub-type="epub">2658-6959</issn><publisher><publisher-name>"Veinard"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29326/2304-196X-2025-14-4-326-336</article-id><article-id custom-type="elpub" pub-id-type="custom">veterinary-954</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ | БОЛЕЗНИ МЕЛКИХ ДОМАШНИХ ЖИВОТНЫХ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS | DISEASES OF SMALL PETS</subject></subj-group></article-categories><title-group><article-title>Хламидиоз кошек (обзор)</article-title><trans-title-group xml:lang="en"><trans-title>Feline chlamydiosis (review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-0702-3024</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Цыганов</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsyganov</surname><given-names>Ilya S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Цыганов Илья Сергеевич, аспирант, ветеринарный врач лаборатории профилактики болезней мелких домашних животных,</p><p>ул. Гвардейская, 6, мкр. Юрьевец, г. Владимир, 600901.</p></bio><bio xml:lang="en"><p>Ilya S. Tsyganov, Postgraduate Student, Veterinarian, Laboratory for Pets Diseases Prevention,</p><p> ul. Gvardeyskaya, 6, Yur’evets, Vladimir 600901.</p></bio><email xlink:type="simple">cyganov@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6434-0683</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щербинин</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shcherbinin</surname><given-names>Sergey V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Щербинин Сергей Владимирович, канд. вет. наук, научный сотрудник информационно-аналитического центра,</p><p>ул. Гвардейская, 6, мкр. Юрьевец, г. Владимир, 600901.</p></bio><bio xml:lang="en"><p>Sergey V. Shcherbinin, Cand. Sci. (Veterinary Medicine), Researcher, Information and Analysis Centre, </p><p>ul. Gvardeyskaya, 6, Yur’evets, Vladimir 600901.</p></bio><email xlink:type="simple">sherbinin@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9494-8537</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галкина</surname><given-names>Т. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Galkina</surname><given-names>Tatyana S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Галкина Татьяна Сергеевна, канд. вет. наук, заведующий лабораторией профилактики болезней мелких домашних животных,</p><p>ул. Гвардейская, 6, мкр. Юрьевец, г. Владимир, 600901.</p></bio><bio xml:lang="en"><p>Tatyana S. Galkina, Cand. Sci. (Veterinary Medicine), Head of Laboratory for Pets Diseases Prevention, </p><p>ul. Gvardeyskaya, 6, Yur’evets, Vladimir 600901.</p></bio><email xlink:type="simple">galkina_ts@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3159-1969</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Груздев</surname><given-names>К. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Gruzdev</surname><given-names>Konstantin N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Груздев Константин Николаевич, д-р биол. наук, профессор, главный научный сотрудник информационно-аналитического центра, </p><p>ул. Гвардейская, 6, мкр. Юрьевец, г. Владимир, 600901.</p></bio><bio xml:lang="en"><p>Konstantin N. Gruzdev, Dr. Sci. (Biology), Professor, Chief Researcher, Information and Analysis Centre, </p><p>ul. Gvardeyskaya, 6, Yur’evets, Vladimir 600901.</p></bio><email xlink:type="simple">gruzdev@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Федеральный центр охраны здоровья животных» (ФГБУ «ВНИИЗЖ»)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Centre for Animal Health</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>21</day><month>12</month><year>2025</year></pub-date><volume>14</volume><issue>4</issue><fpage>326</fpage><lpage>336</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Цыганов И.С., Щербинин С.В., Галкина Т.С., Груздев К.Н., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Цыганов И.С., Щербинин С.В., Галкина Т.С., Груздев К.Н.</copyright-holder><copyright-holder xml:lang="en">Tsyganov I.S., Shcherbinin S.V., Galkina T.S., Gruzdev K.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://veterinary.arriah.ru/jour/article/view/954">https://veterinary.arriah.ru/jour/article/view/954</self-uri><abstract><sec><title>Введение</title><p>Введение. Хламидиоз кошек – болезнь, вызываемая Chlamydia felis, характеризуется конъюнктивитом (одно- или двухсторонним), слезотечением, поражением респираторного и репродуктивного трактов. Данный возбудитель относится к грамотрицательным бактериям со строго облигатным внутриклеточным паразитизмом, однако в начале 40-х гг. ХХ века хламидии считали промежуточным звеном между вирусами и бактериями. До 1960-х гг. из-за малых размеров и неспособности развиваться на искусственных питательных средах хламидии классифицировали как вирусы. Необычный цикл развития, состоящий из двух фаз, позволяет возбудителю долгое время персистировать в организме животного или человека без клинических проявлений. Лечение хламидиоза должно быть системным и затрагивать как этиологическую терапию (применение антибиотиков), так и симптоматическую. Иммунитет против хламидиоза слабый, клеточный иммунитет имеет большее значение, чем гуморальный. В настоящее время на рынке представлены аттенуированные и инактивированные вакцины, позволяющие защитить от клинического проявления болезни, но не от заражения. Распространен хламидиоз практически повсеместно, при этом заметна тенденция к росту выявляемости из года в год.</p></sec><sec><title>Цель исследования</title><p>Цель исследования. Актуализация и систематизация данных по хламидиозу кошек, вызываемому Chlamydia felis.</p></sec><sec><title>Результаты</title><p>Результаты. В статье обозреваются данные о распространенности хламидиоза кошек в мире. Рассмотрены биологические свойс тва описываемого инфекционного агента, клинические признаки хламидиоза кошек и патолого- анатомическая картина, приведены данные об иммунитете, освещаются меры контроля болезни.</p></sec><sec><title>Заключение</title><p>Заключение. Chlamydia felis является распространенным патогеном, способным поражать не только кошек и других животных, но и человека, то есть имеющим зоонозный потенциал. Сложный цикл развития, наличие способности обходить иммунитет хозяина, продолжительная персистенция в организме усложняет его эрадикацию. Длительный курс лечения и переход в хроническую форму снижают качество жизни животных-к омпаньонов и создают угрозу передачи патогена человеку. Для разработки схем успешного лечения и профилактики хламидиоза требуется более детальное практическое изучение Chlamydia felis.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Feline chlamydiosis is a disease caused by Chlamydia felis, it is characterized by conjunctivitis (unilateral or bilateral), lacrimation and lesions of the respiratory and reproductive tracts. This pathogen is a gram-negative bacterium with a strictly obligate intracellular parasitic nature. In the early 1940s, Chlamydia were considered an intermediate link between viruses and bacteria. Until the 1960s, Chlamydia were classified as viruses due to their small size and inability to grow on artificial nutrient media. Their unique two-phase developmental cycle allows the pathogen to persist in the body of an animal or human for a long time without clinical manifestations. Treatment of chlamydiosis must be systemic, addressing both etiological therapy (use of antibiotics) and symptomatic therapy. Immunity against chlamydiosis is weak, with cellular immunity being more important than humoral immunity. Currently, both attenuated and inactivated vaccines are available on the market, which can protect against the clinical manifestation of the disease but not against infection. Chlamydiosis is a globally widespread disease, with detection rates showing a consistent year-on-year increase.</p></sec><sec><title>Objective</title><p>Objective. To review and systematize current data on feline chlamydiosis caused by Chlamydia felis.</p></sec><sec><title>Results</title><p>Results. The article reviews global prevalence data of feline chlamydiosis. It examines the biological properties of the infectious agent, the clinical signs of the disease, and the pathological findings. Data on immunity are presented, and disease control measures are discussed.</p></sec><sec><title>Conclusion</title><p>Conclusion. Chlamydia felis is a worldwide spread pathogen capable of infecting not only cats and other animals but also humans, which indicates its zoonotic potential. Such factors as complex life cycle, adeptness at host immune evasion and ability to establish persistent infections hinder its effective eradication. The required extended treatment regimens and propensity for chronic infections compromise companion animal welfare and pose a risk of transmission to humans.  A more profound understanding of Chlamydia felis pathogenesis is essential for developing effective treatment and prevention strategies.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>обзор</kwd><kwd>хламидиоз кошек</kwd><kwd>Chlamydia felis</kwd><kwd>кошки</kwd></kwd-group><kwd-group xml:lang="en"><kwd>review</kwd><kwd>feline chlamydiosis</kwd><kwd>Chlamydia</kwd><kwd>cats</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена за счет средств ФГБУ «ВНИИЗЖ» в рамках тематики научно-исследовательских работ «Ветеринарное благополучие».</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Sostaric- Zuckermann I. C., Borel N., Kaiser C., Grabarevic Z., Pospischil A. 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