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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">veterinary</journal-id><journal-title-group><journal-title xml:lang="ru">Ветеринария сегодня</journal-title><trans-title-group xml:lang="en"><trans-title>Veterinary Science Today</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-196X</issn><issn pub-type="epub">2658-6959</issn><publisher><publisher-name>"Veinard"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29326/2304-196X-2025-14-1-14-23</article-id><article-id custom-type="elpub" pub-id-type="custom">veterinary-888</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ | БОЛЕЗНИ КРУПНОГО РОГАТОГО СКОТА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS | BOVINE DISEASES</subject></subj-group></article-categories><title-group><article-title>Значение ротавируса, коронавируса и Escherichia coli в этиологии болезней молодняка крупного рогатого скота (обзор)</article-title><trans-title-group xml:lang="en"><trans-title>Role of rotavirus, coronavirus and Escherichia coli in disease etiology in young cattle (review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-5126-4283</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Круглов</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kruglov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Круглов Илья Алексеевич, аспирант, ведущий специалист лаборатории биотехнологии и  конструирования вирусных препаратов </p><p>мкр. Юрьевец, г. Владимир, 600901</p></bio><bio xml:lang="en"><p>Ilya A. Kruglov, Postgraduate Student, Leading Specialist, Laboratory for Biotechnologies and Viral Product Construction</p><p>Yur’evets, Vladimir 600901</p></bio><email xlink:type="simple">kruglov_ia@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5523-3261</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кононов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kononov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кононов Александр Владимирович, д-р вет. наук, заведующий лабораторией  биотехнологии и конструирования вирусных препаратов</p><p>мкр. Юрьевец, г. Владимир, 600901</p></bio><bio xml:lang="en"><p>Aleksandr V. Kononov, Dr. Sci. (Veterinary Medicine), Head of Laboratory for Biotechnologies and Viral Product Construction</p><p>Yur’evets, Vladimir 600901</p></bio><email xlink:type="simple">kononov@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4288-1964</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Нестеров</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nesterov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Нестеров Александр Александрович, канд. вет. наук, заведующий сектором лаборатории биотехнологии и конструирования вирусных препаратов</p><p>мкр. Юрьевец, г. Владимир, 600901</p></bio><bio xml:lang="en"><p>Alexander А. Nesterov, Cand. Sci. (Veterinary Medicine), Head of  Sector, Laboratory for Biotechnologies and Viral Product Construction</p><p>Yur’evets, Vladimir 600901</p></bio><email xlink:type="simple">nesterov@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3932-2416</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кононова</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kononova</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кононова Светлана Владимировна, канд. биол. наук, ведущий научный сотрудник референтной лаборатории болезней крупного рогатого скота</p><p>мкр. Юрьевец, г. Владимир, 600901</p></bio><bio xml:lang="en"><p>Svetlana V. Kononova, Cand. Sci. (Biology), Leading Researcher, Reference Laboratory for Bovine Disease</p><p>Yur’evets, Vladimir 600901</p></bio><email xlink:type="simple">kononova@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3143-7339</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прунтова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pruntova</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Прунтова Ольга Владиславовна, д-р биол. наук, профессор, главный научный сотрудник информационно-аналитического центра</p><p>мкр. Юрьевец, г. Владимир, 600901</p></bio><bio xml:lang="en"><p>Olga V. Pruntova, Dr. Sci. (Biology), Professor, Chief Researcher, Information and Analysis Centre</p><p>Yur’evets, Vladimir 600901</p></bio><email xlink:type="simple">pruntova@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Федеральный центр охраны здоровья животных» (ФГБУ «ВНИИЗЖ»)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Centre for Animal Health</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>20</day><month>03</month><year>2025</year></pub-date><volume>14</volume><issue>1</issue><fpage>14</fpage><lpage>23</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Круглов И.А., Кононов А.В., Нестеров А.А., Кононова С.В., Прунтова О.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Круглов И.А., Кононов А.В., Нестеров А.А., Кононова С.В., Прунтова О.В.</copyright-holder><copyright-holder xml:lang="en">Kruglov I.A., Kononov A.V., Nesterov A.A., Kononova S.V., Pruntova O.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://veterinary.arriah.ru/jour/article/view/888">https://veterinary.arriah.ru/jour/article/view/888</self-uri><abstract><sec><title>Введение</title><p>Введение. Одной из самых распространенных групп патологий, встречающихся у молодняка крупного рогатого скота, являются болезни желудочно-кишечного тракта. Частой их причиной являются возбудители инфекций, среди которых преобладающее значение имеют ротавирус, коронавирус и патогенная форма кишечной палочки.</p></sec><sec><title>Цель исследования</title><p>Цель исследования. Анализ и систематизация актуальной информации о роли рота-, коронавируса и патогенных штаммов Escherichia coli в этиологии болезней крупного рогатого скота, в том числе молодняка, сведений о заболеваемости этими инфекциями на территории Российской Федерации и других стран мира, а также актуальности вакцинопрофилактики против вышеназванных патогенов.</p></sec><sec><title>Результаты</title><p>Результаты. В статье представлена информация о строении ротавируса, коронавируса и Escherichia coli, биологических свойствах возбудителей, факторах, влияющих на форму и тяжесть течения болезней. На основании анализа научной литературы отечественных и зарубежных авторов представлены данные о распространенности колибактериоза, ротавирусной и коронавирусной инфекций, а также описаны основные методы их контроля. Подтверждена важность вакцин для профилактики указанных болезней, перечислены факторы, влияющие на эффективность вакцинопрофилактики, и приведены меры ее повышения.</p></sec><sec><title>Заключение</title><p>Заключение. Средний уровень заболеваемости ротавирусной инфекцией в мире составляет 32,7%, коронавирусной инфекцией – 18,4%, колибактериозом – 39,1%. В России показатель превалентности вышеупомянутых болезней равен 41,4; 33,1 и 30,2% соответственно. Таким образом, в Российской Федерации уровень заболеваемости рота- и коронавирусной инфекциями крупного рогатого скота превышает средний показатель в мире на 8,7 и 14,7% соответственно. Эпизоотическая ситуация по колибактериозу в России благополучнее, чем в большинстве стран: болезнь регистрируется реже среднего мирового значения на 8,9%. Большое генетическое разнообразие и распространенность вышеупомянутых возбудителей требуют комплексного подхода для борьбы с ними. Одним из наиболее эффективных способов является вакцинопрофилактика, что делает разработку эффективных и безопасных вакцинных препаратов против ротавирусной, коронавирусной инфекций и эшерихиоза актуальной задачей.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. One of the most prevalent groups of pathologies detected in young cattle involves gastrointestinal diseases. They are often caused by infectious agents, among which rotavirus, coronavirus and pathogenic Escherichia coli are predominant.</p></sec><sec><title>Objective</title><p>Objective. Analysis and systematization of up-to-date information on the role of rotavirus, coronavirus and pathogenic Escherichia coli strains in the etiology of diseases of cattle, including young animals, data on the incidence of these infections in the Russian Federation and other countries of the world as well as relevance of vaccination against the above-mentioned pathogens.</p></sec><sec><title>Results</title><p>Results. The paper provides information on the structure of rotavirus, coronavirus and Escherichia coli, on the biological properties of the pathogens, and factors affecting the disease form and severity. Based on the analysis of domestic and foreign scientific publications, data on the prevalence of colibacillosis, rotavirus and coronavirus infections are presented, and the main methods of their control are described. The significance of the vaccines for the prevention of these diseases is confirmed, the factors influencing the vaccine prevention effectiveness are listed, and measures to increase it are given.</p></sec><sec><title>Conclusion</title><p>Conclusion. The average global incidence of rotavirus infection is 32.7%, coronavirus infection is 18.4%, and colibacillosis is 39.1%. In Russia, the prevalence rate of the above-mentioned diseasesis 41.4, 33.1 and 30.2%, respectively. Thus, in the Russian Federation, the incidence of bovine rotavirus and coronavirus infections exceeds the global average by 8.7 and 14.7%, respectively. The colibacillosis situation in Russia is better than in most countries: the disease is reported by 8.9% less frequently than the globala verage. High genetic diversity and prevalence of the above-mentioned pathogens require an integrated approach to their control. One of the most effective methods is vaccination, which makes the development of effective and safe vaccines against rotavirus, coronavirus and Escherichia coli infections an urgent task.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>обзор</kwd><kwd>ротавирус</kwd><kwd>коронавирус</kwd><kwd>Escherichia coli</kwd><kwd>молодняк крупного рогатого скота</kwd><kwd>респираторные и кишечные патологии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>review</kwd><kwd>rotavirus</kwd><kwd>coronavirus</kwd><kwd>Escherichia coli</kwd><kwd>young cattle</kwd><kwd>respiratory and intestinal pathologies</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена за счет средств ФГБУ «ВНИИЗЖ» в рамках тематики научно-исследовательских работ «Ветеринарное благополучие».</funding-statement><funding-statement xml:lang="en">Thestudy was fundedbytheFederalCentrefor Animal Health within theresearch topic “VeterinaryWelfare”. For citation: Kruglov I. A., Kononov A. 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