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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">veterinary</journal-id><journal-title-group><journal-title xml:lang="ru">Ветеринария сегодня</journal-title><trans-title-group xml:lang="en"><trans-title>Veterinary Science Today</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-196X</issn><issn pub-type="epub">2658-6959</issn><publisher><publisher-name>"Veinard"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29326/2304-196X-2024-13-4-322-329</article-id><article-id custom-type="elpub" pub-id-type="custom">veterinary-865</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ | ЭПИЗООТОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS | EPIZOOTOLOGY</subject></subj-group></article-categories><title-group><article-title>Астровирусная инфекция животных (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Astrovirus infection in animals (literature review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3751-2168</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мищенко</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mischenko</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мищенко Владимир Александрович, д-р вет. наук, профессор, главный научный сотрудник лаборатории биотехнологий и конструирования вирусных препаратов </p><p>мкр. Юрьевец, г. Владимир, 600901</p></bio><bio xml:lang="en"><p>Vladimir A. Mischenko, Dr. Sci. (Veterinary Medicine), Professor, Chief Researcher, Laboratory for Biotechnologies and Viral Product Construction</p><p>Yur’evets, Vladimir 600901, Russia</p></bio><email xlink:type="simple">mishenko@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9752-6337</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мищенко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mischenko</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мищенко Алексей Владимирович, д-р вет. наук, главный научный сотрудник </p><p>Рязанский проспект, 24/1, г. Москва</p></bio><bio xml:lang="en"><p>Alexey V. Mischenko, Dr. Sci. (Veterinary Medicine), Chief Researcher</p><p>24/1 Ryazansky prospekt, Moscow 109428, Russia</p></bio><email xlink:type="simple">viev@admin.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0959-5915</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никешина</surname><given-names>Т. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikeshina</surname><given-names>Т. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никешина Татьяна Борисовна, канд. биол. наук, заведующий сектором отдела образования и научной информации</p><p>мкр. Юрьевец, г. Владимир, 600901</p></bio><bio xml:lang="en"><p>Tatiana B. Nikeshina, Cand. Sci. (Biology), Head of Sector, Education and Scientific Support Department</p><p>Yur’evets, Vladimir 600901, Russia</p></bio><email xlink:type="simple">nikeshina@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3939-1929</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петрова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrova</surname><given-names>О. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петрова Ольга Николаевна, канд. биол. наук, заместитель заведующего  сектором  информационно-аналитического центра </p><p>мкр. Юрьевец, г. Владимир, 600901</p></bio><bio xml:lang="en"><p>Olga N. Petrova, Cand. Sci. (Biology), Deputy Head of the Sector, Information and Analysis Centre</p><p>Yur’evets, Vladimir 600901, Russia</p></bio><email xlink:type="simple">petrova@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Федеральный центр охраны здоровья животных»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Centre for Animal Health</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ «Федеральный научный центр – Всероссийский научно-исследовательский институт экспериментальной ветеринарии имени К. И. Скрябина и Я. Р. Коваленко Российской академии наук»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Scientific Centre VIEV</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>13</day><month>12</month><year>2024</year></pub-date><volume>13</volume><issue>4</issue><fpage>322</fpage><lpage>329</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мищенко В.А., Мищенко А.В., Никешина Т.Б., Петрова О.Н., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Мищенко В.А., Мищенко А.В., Никешина Т.Б., Петрова О.Н.</copyright-holder><copyright-holder xml:lang="en">Mischenko V.A., Mischenko A.V., Nikeshina Т.B., Petrova О.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://veterinary.arriah.ru/jour/article/view/865">https://veterinary.arriah.ru/jour/article/view/865</self-uri><abstract><p>Во всех странах мира основной причиной массовых гастроэнтеритов новорожденных телят являются возбудители вирусной природы. Диарея в ранний постнатальный период, как основная причина заболеваемости и смертности молодняка, вызывает серьезные проблемы в промышленном скотоводстве и причиняет значительный экономический ущерб. Наиболее распространенными возбудителями вирусного гастроэнтерита у телят являются ротавирусы, коронавирусы и пестивирусы, наряду с которыми все чаще выявляют астровирусы. Представители семейства Astroviridae способны вызывать у животных различные патологии: у птиц – энтерит, гепатит и нефрит, у млекопитающих – гастроэнтерит, неврологические синдромы и энцефалит. Доказана роль данных вирусов в этиологии респираторной патологии животных. Естественными хозяевами астровируса являются: крупный и мелкий рогатый скот, верблюды, олени, яки, косули, буйволы, альпаки, свиньи, дикие кабаны. Возбудитель был выявлен у летучих мышей, грызунов и морских млекопитающих, а также в моллюсках. В настоящее время список животных, восприимчивых к астровирусной инфекции, расширился более чем до 80 видов из 22 семейств, включая домашних, синантропных и диких животных, птиц и млекопитающих, обитающих в наземной и водной среде. В последнее время увеличивается количество свидетельств о появлении изолятов астровируса с рекомбинациями, что способствует возникновению новых генетических вариантов возбудителя. Большое разнообразие видов инфицированных животных, генетическое разнообразие вируса и случаи рекомбинации указывают либо на межвидовую передачу и последующую адаптацию вируса к новым хозяевам, либо на коинфекцию одного и того жехозяина разными генотипами возбудителя, что может приводить к появлению новых астровирусов, способных заражать животных или имеющих зоонозный потенциал. Астровирусная инфекция не обладает клиническими особенностями, позволяющими дифференцировать ее от других кишечных инфекций. Представленные данные указывают на необходимость учета астровирусной инфекции при исследовании проб патологического материала от больных диареей новорожденных телят, ягнят, козлят и поросят в промышленных хозяйствах страны.</p></abstract><trans-abstract xml:lang="en"><p>Viral agents are a major cause of mass gastroenteritides in newborn calves in the countries around the world. Early postnatal diarrhea as the main reason of morbidity and mortality in young animals leads to serious problems in the commercial livestock farming and causes a considerable economic damage. The most common viral gastroenteritis agents in calves are rotaviruses, coronaviruses and pestiviruses, and, along with these, astroviruses are increasingly being detected. The members of the family Astroviridae can cause various pathologies in animals: enteritis, hepatitis and nephritis in birds, gastroenteritis, neurological syndromes and encephalitis in mammals. The role of these viruses in the etiology of respiratory pathology in animals has been demonstrated. The following animals are the natural hosts of astrovirus: cattle, small ruminants, camels, deer, yaks, roe deer, buffaloes, alpacas, pigs, wild boars. The virus has been detected in bats, rodents and marine mammals, as well as in mollusks. Presently, the list of animals susceptible to astrovirus infection has expanded to over 80 species from 22 families, including domestic, synanthropic and wild animals, birds and mammals living in the terrestrial and aquatic environments. In recent times, there has been a lot of evidence of occurrence of recombinant astrovirus isolates, which contributes to the emergence of new genetic variants of the pathogen. A wide variety of infected animal species, the genetic diversity of the virus and the recombination events are indicative either of the cross-species transmission and subsequent adaptation of the virus to new hosts, or of the coinfection of the same host with different virus genotypes, which may lead to the emergence of novel astroviruses that are capable of infecting animals or possess a zoonotic potential. Astrovirus infection has no specific clinical features that allow for its differentiation from other intestinal infections. The presented data highlight the necessity for taking into account astrovirus infection when testing pathological material samples from diarrhea-affected newborn calves, lambs, goat kids and piglets on the commercial farms of the country.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>обзор</kwd><kwd>Astroviridae</kwd><kwd>Avastrovirus</kwd><kwd>Mamastrovirus</kwd><kwd>диарея</kwd><kwd>гастроэнтериты</kwd><kwd>респираторная патология</kwd><kwd>энцефалиты</kwd><kwd>крупный рогатый скот</kwd><kwd>мелкий рогатый скот</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Astroviridae</kwd><kwd>Avastrovirus</kwd><kwd>Mamastrovirus</kwd><kwd>diarrhea</kwd><kwd>gastroenteritis</kwd><kwd>respiratory pathology</kwd><kwd>encephalitis</kwd><kwd>cattle</kwd><kwd>small ruminants</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Актуальные инфекционные болезни крупного рогатого скота: руководство. 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