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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">veterinary</journal-id><journal-title-group><journal-title xml:lang="ru">Ветеринария сегодня</journal-title><trans-title-group xml:lang="en"><trans-title>Veterinary Science Today</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-196X</issn><issn pub-type="epub">2658-6959</issn><publisher><publisher-name>"Veinard"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29326/2304-196X-2024-13-1-36-43</article-id><article-id custom-type="elpub" pub-id-type="custom">veterinary-788</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ | БОЛЕЗНИ ПТИЦ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS | AVIAN DISEASES</subject></subj-group></article-categories><title-group><article-title>Аденовирусные инфекции птиц: многообразие возбудителей, опасность для птицеводства и проблемы иммунопрофилактики (обзор)</article-title><trans-title-group xml:lang="en"><trans-title>Avian adenovirus infections: diversity of pathogens, hazard to poultry industry and problems of immunoprophylaxis (review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-0467-0182</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зеленский</surname><given-names>Ю. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Zelenskiy</surname><given-names>Yu. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зеленский Юрий Романович, ветеринарный фельдшер лаборатории профилактики болезней птиц</p><p>мкр. Юрьевец, г. Владимир, 600901</p></bio><bio xml:lang="en"><p>Yuriy R. Zelenskiy, Paraveterinarian, Laboratory for Avian Diseases Prevention</p><p>Yur’evets, Vladimir 600901</p></bio><email xlink:type="simple">zelenskiy@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8819-0720</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Волков</surname><given-names>М. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Volkov</surname><given-names>M. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Волков Михаил Сергеевич, д-р вет. наук, заведующий лабораторией эпизоотологии и мониторинга</p><p>мкр. Юрьевец, г. Владимир, 600901</p></bio><bio xml:lang="en"><p>Mikhail S. Volkov, Dr. Sci. (Veterinary Medicine), Head of Laboratory for Epizootology and Monitoring</p><p>Yur’evets, Vladimir 600901</p></bio><email xlink:type="simple">volkov_ms@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2084-4484</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Комаров</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Komarov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Комаров Илья Александрович, младший научный сотрудник лаборатории профилактики болезней птиц</p><p>мкр. Юрьевец, г. Владимир, 600901</p></bio><bio xml:lang="en"><p>Ilya A. Komarov, Junior Researcher, Laboratory for Avian Diseases Prevention</p><p>Yur’evets, Vladimir 600901</p></bio><email xlink:type="simple">komarov@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9672-8594</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мороз</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Moroz</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мороз Наталья Владимировна, канд. вет. наук, заведующий лабораторией профилактики болезней птиц</p><p>мкр. Юрьевец, г. Владимир, 600901</p></bio><bio xml:lang="en"><p>Natalya V. Moroz, Cand. Sci. (Veterinary Medicine), Head of Laboratory for Avian Diseases Prevention</p><p>Yur’evets, Vladimir 600901</p></bio><email xlink:type="simple">moroz@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9788-9197</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мудрак</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Mudrak</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мудрак Наталья Станиславовна, д-р биол. наук, главный научный сотрудник референтной лаборатории вирусных болезней птиц</p><p>мкр. Юрьевец, г. Владимир, 600901</p></bio><bio xml:lang="en"><p>Natalia S. Mudrak, Dr. Sci. (Biology), Chief Researcher, Reference Laboratory for Avian Viral Diseases</p><p>Yur’evets, Vladimir 600901</p></bio><email xlink:type="simple">mudrak@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9857-5915</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жбанова</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhbanova</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Жбанова Татьяна Валентиновна, канд. биол. наук, младший научный сотрудник отдела образования и научной информации</p><p>мкр. Юрьевец, г. Владимир, 600901</p></bio><bio xml:lang="en"><p>Tatyana V. Zhbanova, Cand. Sci. (Biology), Junior Researcher, Education and Scientific Support Department </p><p>Yur’evets, Vladimir 600901</p></bio><email xlink:type="simple">zhbanova@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Федеральный центр охраны здоровья животных» (ФГБУ «ВНИИЗЖ»)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal Centre for Animal Health</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>15</day><month>03</month><year>2024</year></pub-date><volume>13</volume><issue>1</issue><fpage>36</fpage><lpage>43</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Зеленский Ю.Р., Волков М.С., Комаров И.А., Мороз Н.В., Мудрак Н.С., Жбанова Т.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Зеленский Ю.Р., Волков М.С., Комаров И.А., Мороз Н.В., Мудрак Н.С., Жбанова Т.В.</copyright-holder><copyright-holder xml:lang="en">Zelenskiy Y.R., Volkov M.S., Komarov I.A., Moroz N.V., Mudrak N.S., Zhbanova T.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://veterinary.arriah.ru/jour/article/view/788">https://veterinary.arriah.ru/jour/article/view/788</self-uri><abstract><p>Представлены данные о многообразии возбудителей аденовирусных инфекций в природе и роли основных патогенов семейства Adenoviridae в инфекционной патологии сельскохозяйственной птицы. Особое внимание уделено проблемным вопросам иммунопрофилактики ввиду отсутствия перекрестного иммунитета между разными серотипами вируса. В мире нет единого и эффективного подхода в стратегии иммунопрофилактики аденовирозов птиц, поэтому совершенствование средств борьбы с аденовирусными заболеваниями птиц является актуальной и важной задачей. Аденовирусные инфекции птиц представлены разными нозологическими единицами: синдромом снижения яйценоскости, синдромом гидроперикардита кур, эрозией желудка, болезнью мраморной селезенки фазанов, геморрагическим энтеритом индеек, гепатитом с тельцами-включениями и множеством неклассифицированных болезней. Приводится информация об основных нозологических формах аденовирусных инфекций, представляющих угрозу для рентабельного ведения птицеводства, освещены результаты исследований зарубежных авторов по изучению эффективности некоторых вакцин против аденовирозов. Большинство вакцин разработаны для профилактики синдрома гидроперикардита кур, однако существование множества серотипов возбудителя требует создания эффективных средств профилактики и диагностики в целях контроля и других инфекций, вызываемых аденовирусами. Нет ни одной зарегистрированной вакцины против аденовирусных инфекций, вызывающих гепатит с тельцами-включениями и эрозию желудка. При этом на долю только гепатита с тельцами-включениями приходится 2,9% от всех регистрируемых инфекционных заболеваний птиц. Вакцин, зарегистрированных на территории Российской Федерации, недостаточно для полного контроля данных инфекций, что требует своевременного решения проблемы. Многообразие возбудителей аденовирусных инфекций птиц обусловливает проблематику их дифференциальной диагностики и специфической профилактики.</p></abstract><trans-abstract xml:lang="en"><p>The data on diversity of adenovirus pathogens in nature and the role of the main representatives of the Adenoviridae family in poultry infectious pathology are presented. Special attention is paid to problematic issues of immunoprophylaxis due to lack of cross-immunity between different virus serotypes. There is no single and effective approach in the global strategy of immunoprophylaxis of avian adenoviruses, therefore, improving the means of avian adenovirus disease control is an urgent and important task. Avian adenovirus infections are represented by different nosological units: egg drop syndrome, hydropericardium syndrome, adenoviral gizzard erosion, marbled spleen disease of pheasants, hemorrhagic enteritis of turkeys, inclusion body hepatitis and many unclassified diseases. The paper provides data on the main nosological forms of adenovirus infections that pose a threat to cost-effective poultry farming, and highlights test results obtained by foreign authors on the effectiveness of some vaccines against adenovirus infection. Most vaccines have been developed to prevent avian hydropericardium syndrome, however, occurrence of many virus serotypes requires effective means of prevention and diagnosis in order to control other infections caused by adenoviruses. There is no registered vaccine against adenovirus infections that cause inclusion body hepatitis and adenoviral gizzard erosion. At the same time, inclusion body hepatitis alone accounts for 2.9% of all recorded avian infectious diseases. Vaccines registered in the Russian Federation are not enough to fully control these infections, and that requires a timely solution to the problem. The variety of avian adenoviruses determines the problems of their differential diagnosis and specific prevention.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>обзор</kwd><kwd>аденовирусные инфекции птиц</kwd><kwd>Aviadenovirus</kwd><kwd>Atadenovirus</kwd><kwd>Siadenovirus</kwd></kwd-group><kwd-group xml:lang="en"><kwd>review</kwd><kwd>avian adenovirus infections</kwd><kwd>Aviadenovirus</kwd><kwd>Atadenovirus</kwd><kwd>Siadenovirus</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена за счет средств ФГБУ «ВНИИЗЖ» в рамках тематики научно-исследовательских работ «Ветеринарное благополучие».</funding-statement><funding-statement xml:lang="en">The study was funded by the FGBI “ARRIAH” within the research topic “Veterinary Welfare”.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бурмистров А. 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