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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">veterinary</journal-id><journal-title-group><journal-title xml:lang="ru">Ветеринария сегодня</journal-title><trans-title-group xml:lang="en"><trans-title>Veterinary Science Today</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-196X</issn><issn pub-type="epub">2658-6959</issn><publisher><publisher-name>"Veinard"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29326/2304-196X-2023-12-4-303-307</article-id><article-id custom-type="elpub" pub-id-type="custom">veterinary-765</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ | БОЛЕЗНИ МЕЛКИХ ДОМАШНИХ ЖИВОТНЫХ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS | DISEASES OF SMALL PETS</subject></subj-group></article-categories><title-group><article-title>Панлейкопения кошек (обзор)</article-title><trans-title-group xml:lang="en"><trans-title>Feline panleukopenia (review)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3921-8050</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Киселев</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kiselev</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Киселев Алексей Максимович, аспирант, ветеринарный врач лаборатории профилактики болезней мелких домашних животных</p><p>600901, г. Владимир, мкр. Юрьевец</p></bio><bio xml:lang="en"><p>Alexey M. Kiselev, Postgraduate Student, Veterinarian, Laboratory for Pets Disease Prevention</p><p>600901, Vladimir, Yur’evets</p></bio><email xlink:type="simple">kiselev_am@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6434-0683</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Щербинин</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shcherbinin</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Щербинин Сергей Владимирович, кандидат ветеринарных наук, научный сотрудник информационно-аналитического центра</p><p>г. Владимир</p></bio><bio xml:lang="en"><p>Sergey V. Shcherbinin, Candidate of Science (Veterinary Medicine), Researcher, Information and Analysis Centre</p><p>Vladimir</p></bio><email xlink:type="simple">sherbinin@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9494-8537</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Галкина</surname><given-names>Т. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Galkina</surname><given-names>T. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Галкина Татьяна Сергеевна, кандидат ветеринарных наук, заведующий лабораторией профилактики болезней мелких домашних животных</p><p>г. Владимир</p></bio><bio xml:lang="en"><p>Tatyana S. Galkina, Candidate of Science (Veterinary Medicine), Head of Laboratory for Pets Disease Prevention</p><p>Vladimir</p></bio><email xlink:type="simple">galkina_ts@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «Федеральный центр охраны здоровья животных» (ФГБУ «ВНИИЗЖ»)</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FGBI “Federal Centre for Animal Health” (FGBI “ARRIAH”)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>19</day><month>12</month><year>2023</year></pub-date><volume>12</volume><issue>4</issue><fpage>303</fpage><lpage>307</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Киселев А.М., Щербинин С.В., Галкина Т.С., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Киселев А.М., Щербинин С.В., Галкина Т.С.</copyright-holder><copyright-holder xml:lang="en">Kiselev A.M., Shcherbinin S.V., Galkina T.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://veterinary.arriah.ru/jour/article/view/765">https://veterinary.arriah.ru/jour/article/view/765</self-uri><abstract><p>Панлейкопения кошек – болезнь, известная в мире сначала прошлого века и первоначально отнесенная к чуме плотоядных, – с момента обнаружения расширила круг своих хозяев в результате успешных заражений (как в естественных условиях, так и искусственных) куньих, енотовых и даже приматов. Эволюционно возбудитель заболевания дал начало новому инфекционному агенту – парвовирус у собак, который, несмотря на ДНК-архитектуру, демонстрирует сравнительно высокую скорость мутаций и появление новых вариантов. Болезнь в большинстве случаев смертельна для новорожденных котят и вызывает сильные страдания взрослых кошек, тяжело поражая жизненно важные системы организма. Исход часто (до 50%) неблагоприятный, причем возраст кошки играет одну из ключевых ролей. Существующие меры профилактики способны защитить животных, однако вакцинные препараты используются при отсутствии адекватных испытаний на кошках и собаках (по этическим соображениям) и имеют ряд ограничений в применении. Устойчивость инфекционного агента в окружающей среде и растущее число безнадзорных животных позволяют беспрепятственно циркулировать возбудителю инфекции в данных популяциях, угрожая благополучию домашних кошек, а также вымирающих кошачьих в заповедниках и зоопарках. Послабления в законодательстве, регуляция численности безнадзорных животных, адекватная профилактика среди целевых групп в приютах, питомниках и зоопарках могут способствовать значительному снижению циркуляции возбудителей не только данной болезни, но и большинства других опасных инфекций, например бешенства, ринотрахеита кошек, чумы плотоядных идругих, в подверженных риску популяциях животных.</p></abstract><trans-abstract xml:lang="en"><p>Feline panleukopenia, a disease globally known since the beginning of the last century and originally attributed to canine distemper, has expanded its range of hosts since its discovery as a result of successful infections (both natural and experimental) in mustelids, raccoons and even primates. Evolutionarily, the disease pathogen gave rise to anew infectious agent– canine parvovirus, which, despite its DNA structure, demonstrates a relatively high mutation rate and the emergence of new variants. The disease is in most cases fatal to newborn kittens and causes severe manifestations in adult cats, severely aﬀecting the vital systems of the body. The prognosis is often (up to50%) unfavorable, while the animal’s age plays a key role. Current preventive measures can ensure protection, however, vaccines are used in the absence of adequate testing on cats and dogs (for ethical reasons) and have a number of limitations in use. The persistence of the infectious agent in the environment and the growing number of stray animals allow the infectious agent to circulate unhindered in these populations, threatening the health of domestic cats and endangered felines in nature reserves and zoos. Easing of legislation for leading research centers, regulation of the number of stray animals, adequate prevention measures for target groups in animal shelters, nurseries and zoos can contribute to a signiﬁcant reduction in the circulation insusceptible populations of pathogens not only of this disease, but also of the majority of other dangerous infections, such as rabies, feline rhinotracheitis, canine distemper and others.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>обзор</kwd><kwd>панлейкопения кошек</kwd><kwd>парвовирусы</kwd><kwd>кошачьи</kwd></kwd-group><kwd-group xml:lang="en"><kwd>review</kwd><kwd>feline panleukopenia</kwd><kwd>parvoviruses</kwd><kwd>Felidae</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена за счет средств ФГБУ «ВНИИЗЖ» в рамках тематики научно-исследовательских работ «Ветеринарное благополучие».</funding-statement><funding-statement xml:lang="en">The study was fundedby the FGBI “ARRIAH” within the framework of “VeterinaryWelfare” research work.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Horlacher K. 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