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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">veterinary</journal-id><journal-title-group><journal-title xml:lang="ru">Ветеринария сегодня</journal-title><trans-title-group xml:lang="en"><trans-title>Veterinary Science Today</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-196X</issn><issn pub-type="epub">2658-6959</issn><publisher><publisher-name>"Veinard"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29326/2304-196X-2021-10-4-349-356</article-id><article-id custom-type="elpub" pub-id-type="custom">veterinary-598</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЩИЕ ВОПРОСЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GENERAL ISSUES</subject></subj-group></article-categories><title-group><article-title>Влияние хлореллы на гематологические показатели и биодоступность питательных веществ рациона  у макаков-резусов</article-title><trans-title-group xml:lang="en"><trans-title>Effect of Chlorella on hematological parameters and nutrient bioavailability in the diet of rhesus monkeys (Macaca mulatta)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5086-7943</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гапонов</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gaponov</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гапонов Николай Васильевич, кандидат биологических наук, старший научный сотрудник</p><p>г. Сочи</p></bio><bio xml:lang="en"><p>Nikolay V. Gaponov, Candidate of Science (Biology), Senior Researcher</p><p>Sochi</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1294-751X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панченко</surname><given-names>Ал. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Panchenko</surname><given-names>Al. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Панченко Алла Вячеславовна, кандидат медицинских наук, ведущий научный сотрудник лаборатории молекулярной биологии </p><p>г. Сочи</p></bio><bio xml:lang="en"><p>Alla V. Panchenko, Candidate of Science (Medical), Leading Researcher, Laboratory of Molecular Biology</p><p>Sochi</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5346-7646</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Панченко</surname><given-names>Ан. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Panchenko</surname><given-names>An. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Панченко Андрей Владимирович, доктор медицинских наук, главный научный сотрудник лаборатории молекулярной биологии </p><p>г. Сочи</p></bio><bio xml:lang="en"><p>Andrey V. Panchenko, Doctor of Science (Medical), Chief Researcher, Laboratory of Molecular Biology</p><p>Sochi</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8111-2298</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чугуев</surname><given-names>Ю. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Chuguev</surname><given-names>Yu. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чугуев Юрий Петрович, кандидат биологических наук, ведущий научный сотрудник </p><p>г. Сочи</p></bio><bio xml:lang="en"><p>Yuri P. Chuguev, Candidate of Science (Biology), Leading Researcher</p><p>Sochi</p><p> </p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Всероссийский научно-исследовательский институт люпина – филиал ФГБНУ «Федеральный научный центр кормопроизводства и агроэкологии имени В. Р. Вильямса»; ФГБНУ «Научно-исследовательский институт медицинской приматологии»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>All-Russian Lupine Research Institute – Branch of the Federal Williams Research Center of Forage Production and Agroecology; FSBSI “Research Institute of Medical Primatology”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ «Научно-исследовательский институт медицинской приматологии»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSBSI “Research Institute of Medical Primatology”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>19</day><month>11</month><year>2021</year></pub-date><volume>10</volume><issue>4</issue><fpage>349</fpage><lpage>356</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гапонов Н.В., Панченко А.В., Панченко А.В., Чугуев Ю.П., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Гапонов Н.В., Панченко А.В., Панченко А.В., Чугуев Ю.П.</copyright-holder><copyright-holder xml:lang="en">Gaponov N.V., Panchenko A.V., Panchenko A.V., Chuguev Y.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://veterinary.arriah.ru/jour/article/view/598">https://veterinary.arriah.ru/jour/article/view/598</self-uri><abstract><p>Хлорелла обладает широким спектром биологической активности, в частности, проявляет выраженную антиоксидантную активность, противовоспалительные, противоопухолевые и противовирусные свойства. Изучению кормовых достоинств этой одноклеточной зеленой водоросли при использовании в составе рационов для сельскохозяйственных животных посвящен ряд исследований, однако вопрос возможности включения разных видов Chlorella в рацион приматов практически не изучен. Целью данной работы была оценка возможности замещения высокопротеиновых кормов животного и растительного происхождения на хлореллу, определение коэффициентов переваримости питательных веществ рационов и влияния сухой и суспензионной форм водоросли на гематологические, биохимические показатели крови у самцов макаков-резусов. Полученные при проведении эксперимента данные свидетельствуют о том, что включение в рацион хлореллы как в сухом виде, так и в виде клеточной суспензии способствует лучшей усвояемости питательных веществ. Так, в группе животных, получавших суспензию водоросли, усвояемость сырого протеина увеличилась на 4,18% (p &lt; 0,05), сырого жира – на 4,70% (p &lt; 0,01), сырой клетчатки – на 4,14% (p &lt; 0,05) и сырой золы – на 12,32% (p &lt; 0,001). У приматов, в рецептуру комбикорма которых был введен порошок хлореллы, коэффициенты переваримости сырого протеина были выше на 6,83% (p &lt; 0,001), сырой клетчатки – на 4,78% (p &lt; 0,05) и сырой золы – на 18,93% (p &lt; 0,001). Результаты гематологических исследований указывают на отсутствие побочных эффектов от длительного употребления хлореллы приматами. Введение в рацион сухой хлореллы способствовало повышению уровня глюкозы в крови до верхней границы контрольных значений, тогда как суспензия хлореллы не оказывала такого эффекта. Таким образом, хлорелла может быть успешно использована в качестве компонента сбалансированного лабораторного рациона для приматов или в качестве кормовой добавки.</p></abstract><trans-abstract xml:lang="en"><p>Chlorella shows a wide spectrum of biological activity, in particular, it exhibits a pronounced antioxidant activity and demonstrates anti-inflammatory, antitumor and antiviral properties. A number of research works have been devoted to studying feed advantages of this unicellular green algae when used in the diets of livestock animals, but the possibility of including different Chlorella species in the diet of primates has not been practically studied. The aim of this work was to assess the possibility of replacing high-protein animal and vegetable feeds with Chlorella, to calculate the digestibility coefficients for the diet nutrients and the effect of algal dry and suspension forms on hematological and serum biochemical parameters in male rhesus monkeys. The data obtained during the experiment indicate that the inclusion of Chlorella in the diet both in the dry form and cell suspension improves nutrient digestibility. Thus, the digestibility of crude protein in the animals receiving algae suspension increased by 4.18% (p &lt; 0.05), that of crude fat – by 4.70% (p &lt; 0.01), crude fiber – by 4.14% (p &lt; 0.05) and crude ash – by 12.32% (p &lt; 0.001). The digestibility coefficients of crude protein in the primates receiving compound feed supplemented with Chlorella powder were higher by 6.83% (p &lt; 0.001), those of crude fiber – by 4.78% (p &lt; 0.05) and crude ash – by 18.93% (p &lt; 0.001) The hematological study results indicate the absence of side effects from long-term Chlorella consumption by primates. The introduction of dry Chlorella into the diet increased blood glucose levels to the upper limit of the control values, while Chlorella suspension did not produce this effect. Thus, Chlorella can be successfully used as a component of a balanced laboratory diet for primates or as a feed additive.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хлорелла</kwd><kwd>переваримость</kwd><kwd>состав крови</kwd><kwd>биохимический анализ крови</kwd><kwd>суспензия</kwd><kwd>приматы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Chlorella</kwd><kwd>digestibility</kwd><kwd>blood composition</kwd><kwd>biochemical blood test</kwd><kwd>suspension</kwd><kwd>primates</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Liu J., Chen F. Biology and industrial applications of Chlorella: Advances and prospects. Adv. Biochem. Eng. Biotechnol. 2016; 153: 1–35. DOI: 10.1007/10_2014_286.</mixed-citation><mixed-citation xml:lang="en">Liu J., Chen F. Biology and industrial applications of Chlorella: Advances and prospects. Adv. Biochem. Eng. Biotechnol. 2016; 153: 1–35. 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