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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">veterinary</journal-id><journal-title-group><journal-title xml:lang="ru">Ветеринария сегодня</journal-title><trans-title-group xml:lang="en"><trans-title>Veterinary Science Today</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-196X</issn><issn pub-type="epub">2658-6959</issn><publisher><publisher-name>"Veinard"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29326/2304-196X-2018-2-25-57-60</article-id><article-id custom-type="elpub" pub-id-type="custom">veterinary-363</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЩИЕ ВОПРОСЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GENERAL ISSUES</subject></subj-group></article-categories><title-group><article-title>ВЛИЯНИЕ ПРЕПАРАТА «ВЕТОМ 21.77» НА БИОХИМИЧЕСКИЙ ПРОФИЛЬ СЫВОРОТКИ КРОВИ МЫШЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>EFFECT  OF "VETOM 21.77" PREPARATION  ON SERUM BIOCHEMICAL PATTERN IN MICE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рафикова</surname><given-names>Э. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Rafikova</surname><given-names>E. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аспирант.</p><p>Новосибирск</p></bio><bio xml:lang="en"><p>Post-Graduate Student.</p></bio><email xlink:type="simple">pchelka_leta@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО Новосибирский ГАУ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FGBEE Novosibirsk Agricultural University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>03</day><month>07</month><year>2018</year></pub-date><volume>0</volume><issue>2</issue><fpage>57</fpage><lpage>60</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Рафикова Э.Р., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Рафикова Э.Р.</copyright-holder><copyright-holder xml:lang="en">Rafikova E.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://veterinary.arriah.ru/jour/article/view/363">https://veterinary.arriah.ru/jour/article/view/363</self-uri><abstract><p>Известно, что хищные грибы-гифомицеты играют важную роль в системе профилактических мероприятий при гельминтозах. Отмечено, что сведения о свойствах и влиянии на организм животных соединений, содержащихся в хищных грибах, немногочисленны. Представлены результаты исследования по определению влияния нового микробиологического препарата «Ветом 21.77» на основе Duddingtonia flagrans на биохимический профиль сыворотки крови лабораторных мышей. Препарат назначали животным в дозах 2, 5, 50 и 300 мкл/кг массы. Контроль изучаемых показателей производили до исследования, через 2 и 7 сут после ежедневного применения препарата. Во всех опытных группах показатели сохранялись в пределах физиологической нормы, как и в контрольной, где препарат не применяли. Результаты исследования свидетельствуют о безвредности микробиологического препарата. У мышей, получающих максимальную дозу препарата, регистрировали достоверное увеличение содержания общего белка и альбумина в сравнении с аналоговыми из контроля.</p></abstract><trans-abstract xml:lang="en"><p>It is known that predatory Hyphomycetes fungi play an important role in measures taken for helminthic infestation prevention. There is little evidence on properties of compounds contained in predatory fungi and their effect on animals. Results of tests of "Vetom 21.77", new microbiological preparation based on Duddingtonia flagrans, for its effect on serum biochemical pattern of laboratory mice are presented. The preparation was administered to the animals at the dose of 2, 5, 50 and 300 µl/kg of body weight. The animals were examined for tested parameters prior and 2 and 7 days after daily administration of the preparation. The parameters remained within the normal physiological limits in all test group as well as in control group not given the preparation. The test results indicated safety of the said microbiological preparation. Significant increase in total protein and albumin contents was recorded in mice given the maximum dose of the preparation as compared with those of control group.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>«Ветом»</kwd><kwd>биохимический профиль</kwd><kwd>мыши</kwd><kwd>Duddingtonia flagrans</kwd></kwd-group><kwd-group xml:lang="en"><kwd>"Vetom"</kwd><kwd>biochemical pattern</kwd><kwd>mice</kwd><kwd>Duddingtonia flagrans</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Беккер З. Э. Физиология и биохимия грибов. – М.: Изд-во Моск. ун-та, 1988. – 230 с.</mixed-citation><mixed-citation xml:lang="en">Becker Z. E. Physiology and biochemistry of fungi [Fiziologija i biohimija gribov]. 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