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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">veterinary</journal-id><journal-title-group><journal-title xml:lang="ru">Ветеринария сегодня</journal-title><trans-title-group xml:lang="en"><trans-title>Veterinary Science Today</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-196X</issn><issn pub-type="epub">2658-6959</issn><publisher><publisher-name>"Veinard"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29326/2304-196X-2018-2-25-13-17</article-id><article-id custom-type="elpub" pub-id-type="custom">veterinary-355</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>БОЛЕЗНИ СВИНЕЙ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PORCINE DISEASES</subject></subj-group></article-categories><title-group><article-title>ИЗУЧЕНИЕ АНТИГЕННОЙ АКТИВНОСТИ АССОЦИИРОВАННЫХ ВАКЦИН  ПРОТИВ БОЛЕЗНИ АУЕСКИ, РЕПРОДУКТИВНО-РЕСПИРАТОРНОГО СИНДРОМА И ПАРВОВИРУСНОЙ ИНФЕКЦИИ СВИНЕЙ</article-title><trans-title-group xml:lang="en"><trans-title>TESTING OF COMBINED VACCINES AGAINST AUJEZSKY’S DISEASE, PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME AND PORCINE PARVOVIRUS INFECTION FOR THEIR ANTIGENICITY</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баборенко</surname><given-names>Е. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Baborenko</surname><given-names>Ye. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Старший научный сотрудник, кандидат биологических наук.</p><p>Владимир</p></bio><bio xml:lang="en"><p>Senior Researcher, Candidate of Science (Biology).</p><p>Vladimir</p></bio><email xlink:type="simple">baborenko@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Долганова</surname><given-names>Е. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Dolganova</surname><given-names>Ye. K.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Старший научный сотрудник, кандидат ветеринарных наук.</p><p>Владимир</p></bio><bio xml:lang="en"><p>Senior Researcher, Candidate of Science (Veterinary Medicine).</p><p>Vladimir</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Груздев</surname><given-names>К. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Gruzdev</surname><given-names>K. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Главный научный сотрудник, доктор биологических наук, профессор.</p><p>Владимир</p></bio><bio xml:lang="en"><p>Chief Researcher, Doctor of Science (Biology), Professor.</p><p>Vladimir</p></bio><email xlink:type="simple">gruzdev@arriah.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБУ «ВНИИЗЖ», г. Владимир</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FGBI "ARRIAH", Vladimir</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>02</day><month>07</month><year>2018</year></pub-date><volume>0</volume><issue>2</issue><fpage>13</fpage><lpage>17</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Баборенко Е.П., Долганова Е.К., Груздев К.Н., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Баборенко Е.П., Долганова Е.К., Груздев К.Н.</copyright-holder><copyright-holder xml:lang="en">Baborenko Y.P., Dolganova Y.K., Gruzdev K.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://veterinary.arriah.ru/jour/article/view/355">https://veterinary.arriah.ru/jour/article/view/355</self-uri><abstract><p>Представлены исследования по изучению антигенных свойств вакцины против болезни Ауески из маркированного штамма, репродуктивнореспираторного синдрома свиней инактивированной эмульгированной, вакцины против болезни Ауески из маркированного штамма и парвовирусной инфекции свиней инактивированной эмульгированной производства ФГБУ «ВНИИЗЖ». Показано, что биопрепараты могут успешно использоваться в целях профилактики репродуктивно-респираторного комплекса заболеваний, парвовирусной инфекции свиней и болезни Ауески. Особую значимость они приобретают при использовании в программах по контролю и искоренению болезни Ауески. Применение вакцины из маркированного штамма вируса болезни Ауески дает возможность дифференцировать животных, имеющих в сыворотках крови антитела к маркированному вакцинному штамму (по отсутствию антител к гликопротеину gE в 100% случаев), от животных с антителами к полевым штаммам вируса болезни Ауески. Комплексная оценка применения ассоциированных вакцин, разработанных в ФГБУ «ВНИИЗЖ» (болезнь Ауески из маркированного штамма, репродуктивно-респираторный синдром, парвовирусная инфекция), в системе противоэпизоотических мероприятий в одном из свиноводческих хозяйств Российской Федерации показала их безвредность, высокую антигенную активность, иммуногенность.</p></abstract><trans-abstract xml:lang="en"><p>Tests of inactivated emulsion anti-Aujezsky’s disease, porcine reproductive and respiratory syndrome (PRRS) vaccine based on marker Aujezsky’s disease virus strain, PRRS virus strain and inactivated emulsion anti-Aujezsky’s disease and porcine parvovirus infection vaccine based on marker Aujezsky’s disease virus strain and porcine parvovirus strain developed by the FGBI “ARRIAH” for their antigenicity are described in the paper. It is demonstrated that the said vaccines can be used successfully for PRRS and porcine parvovirus infection and Aujezsky’s disease prevention. They are becoming of special significance when used in programs on Aujeszky’s disease control and eradication. The use of the vaccine based on marker Aujeszky’s disease virus strain allows differentiation between the animals that have antibodies to the marker vaccine strain (in the absence of antibodies to the glycoprotein gE in 100% of cases) from the animals with antibodies to field strains of the Aujeszky’s disease virus in their sera. A comprehensive assessment of the use of associated vaccines developed in the FGBI “ARRIAH” (against Aujeszky’s disease based on the marker strain, reproductive and respiratory syndrome, parvovirus infection), in the framework of anti-epidemic measures on a pig farm of the Russian Federation showed their safety, high antigenicity, immunogenicity.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>болезнь Ауески</kwd><kwd>маркированный штамм</kwd><kwd>репродуктивно-респираторный синдром свиней</kwd><kwd>парвовирусная инфекция свиней</kwd><kwd>антигенность</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Aujezsky’s disease</kwd><kwd>marker virus strain</kwd><kwd>porcine reproductive and respiratory syndrome</kwd><kwd>porcine parvovirus infection</kwd><kwd>antigenicity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Кодекс здоровья наземных животных. Т. 2. 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