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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">veterinary</journal-id><journal-title-group><journal-title xml:lang="ru">Ветеринария сегодня</journal-title><trans-title-group xml:lang="en"><trans-title>Veterinary Science Today</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2304-196X</issn><issn pub-type="epub">2658-6959</issn><publisher><publisher-name>"Veinard"</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">veterinary-275</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ДРУГИЕ БОЛЕЗНИ</subject></subj-group></article-categories><title-group><article-title>Вакцинные масляные адъюванты для развития аквакультуры</article-title><trans-title-group xml:lang="en"><trans-title>Vaccine oil adjuvants for the development of aquaculture</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Arous</surname><given-names>J. B.</given-names></name><name name-style="western" xml:lang="en"><surname>Arous</surname><given-names>J. B.</given-names></name></name-alternatives><email xlink:type="simple">Juliette.BENAROUS@airliquide.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Dupuis</surname><given-names>L. .</given-names></name><name name-style="western" xml:lang="en"><surname>Dupuis</surname><given-names>L. .</given-names></name></name-alternatives><email xlink:type="simple">laurent.dupuis@airliquide.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>SEPPIC</institution><country>Россия</country></aff><aff xml:lang="en"><institution>SEPPIC</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>02</day><month>04</month><year>2018</year></pub-date><volume>0</volume><issue>4</issue><fpage>62</fpage><lpage>65</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Arous J.B., Dupuis L..., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Arous J.B., Dupuis L...</copyright-holder><copyright-holder xml:lang="en">Arous J.B., Dupuis L...</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://veterinary.arriah.ru/jour/article/view/275">https://veterinary.arriah.ru/jour/article/view/275</self-uri><abstract><p>Сельское хозяйство является быстроразвивающейся отраслью, которая на сегодняшний день производит более 30 видов рыб. Развитию аквакультурной отрасли в течение последних десятилетий способствовала разработка инъекционных вакцин на основе масляного адъюванта, что позволило обеспечить длительную защиту рыб и значительно снизить использование антибиотиков. Сегодня инъекционные вакцины для рыб вводятся внутрибрюшинно, и в них обычно добавляется масляный адъювант для эмульсионных вакцин. Montanide“ ISA 763А VG является адъювантом без минерального масла, который широко использовался для вакцинации разнообразных видов рыб (лосось, форель, сибас, тилапия и т.д.). Также рассматриваются другие способы введения вакцины, такие как погружение или пероральное введение. Для этого разрабатываются новые адъюванты и составы.</p></abstract><trans-abstract xml:lang="en"><p>Aquaculture is a fast growing industry, which produces today more than 30 species of fish. The growth of aquaculture in the last decades has been supported by the development of oil adjuvanted injectable vaccines that allowed a long term protection offish and a strong reduction of the use of antibiotics. Today, injectable vaccines for fish are administered through intraperitoneal injection and are usually adjuvanted with water in oil emulsion adjuvants. Montanide“ ISA 763 AVG is a non mineral oil based adjuvant which has been extensively used for vaccination of diverse fish species (salmon, trout, seabass, tilapia, ect.). Other routes of administration such as immersion and oral administration are also considered and new adjuvants and formulations are being developed for these applications.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>Fish vaccines</kwd><kwd>aquaculture</kwd><kwd>adjuvants</kwd><kwd>Montanide“</kwd><kwd>вакцины для рыб</kwd><kwd>аквакультура</kwd><kwd>адъюванты</kwd><kwd>Montanide“</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">CaoT.T.,Tsai M.A.,Yang C.D.,Wang P.C., KuoT.Y., HSU-CHUNG GABRIEL Chen H.C.G.S., Chen S.C. Vaccine efficacy of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from Edwardsiella ictaluri against E. tarda in tilapia //J. Gen. Appl. Microbiol. - 2014. -Vol.60. - P. 241-250.</mixed-citation><mixed-citation xml:lang="en">CaoT.T.,Tsai M.A.,Yang C.D.,Wang P.C., KuoT.Y., HSU-CHUNG GABRIEL Chen H.C.G.S., Chen S.C. Vaccine efficacy of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from Edwardsiella ictaluri against E. tarda in tilapia //J. Gen. Appl. Microbiol. - 2014. -Vol.60. - P. 241-250.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Castro N., Toranzo A.E., Nunez S., Magarinos B. Development of an effective Edwardsiella tarda vaccine for cultured turbot (Scophthalmus maximus) // Fish Shellfish Immunol. - 2008. - Vol. 25 (3). - P. 208-212.</mixed-citation><mixed-citation xml:lang="en">Castro N., Toranzo A.E., Nunez S., Magarinos B. Development of an effective Edwardsiella tarda vaccine for cultured turbot (Scophthalmus maximus) // Fish Shellfish Immunol. - 2008. - Vol. 25 (3). - P. 208-212.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Jaafar R.M., Chettri J.K., Dalsgaard Al-Jubury A., Kania P.W., Skov J., Buchmann K. Effects of adjuvant Montanide™ ISA 763 AVG in rainbow trout injection vaccinated against Yersinia ruckeri//Fish Shellfish Immunol.-2015.-Vol.47.-P. 797-806.</mixed-citation><mixed-citation xml:lang="en">Jaafar R.M., Chettri J.K., Dalsgaard Al-Jubury A., Kania P.W., Skov J., Buchmann K. Effects of adjuvant Montanide™ ISA 763 AVG in rainbow trout injection vaccinated against Yersinia ruckeri//Fish Shellfish Immunol.-2015.-Vol.47.-P. 797-806.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Fish Vaccines. A short, but remarkable journey / P. Smith //Veterinary Vaccines conference, 3-4 December, 2014, Brussels, Belgium.</mixed-citation><mixed-citation xml:lang="en">Fish Vaccines. A short, but remarkable journey / P. Smith //Veterinary Vaccines conference, 3-4 December, 2014, Brussels, Belgium.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Soltani M., Shafiei S.H., Yosefi P., Mosavi S.H., Mokhtari A. Effect of Montanide IMS 1312VG adjuvant on efficacy of Yersinia ruckeri vaccine in rainbow trout (On-corhynchus mykiss) // Fish Shellfish Immunol. - 2014. -Vol. 37. P. 60-65.</mixed-citation><mixed-citation xml:lang="en">Soltani M., Shafiei S.H., Yosefi P., Mosavi S.H., Mokhtari A. Effect of Montanide IMS 1312VG adjuvant on efficacy of Yersinia ruckeri vaccine in rainbow trout (On-corhynchus mykiss) // Fish Shellfish Immunol. - 2014. -Vol. 37. P. 60-65.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Sommerset I., Krossoy B., Biering E., Frost P. Vaccines for fish in aquaculture // Expert Rev. Vaccines. - 2005. -Vol. 4.-P. 89-101.</mixed-citation><mixed-citation xml:lang="en">Sommerset I., Krossoy B., Biering E., Frost P. Vaccines for fish in aquaculture // Expert Rev. Vaccines. - 2005. -Vol. 4.-P. 89-101.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Tafalla C., Bogwald J., Dalmo A.R. Adjuvants and immunostimulants in fish vaccines: Current knowledge and future perspectives // Fish Shellfish Immunol. - 2013. -Vol. 35 (6).-P. 1740-1750.</mixed-citation><mixed-citation xml:lang="en">Tafalla C., Bogwald J., Dalmo A.R. Adjuvants and immunostimulants in fish vaccines: Current knowledge and future perspectives // Fish Shellfish Immunol. - 2013. -Vol. 35 (6).-P. 1740-1750.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Tobar I., Arancibia S.,Torres C., Vera V., Soto P., Carrasco C., Alvarado M., Neira E., Arcos S.,Tobar J.A. Successive oral immunizations against Piscirickettsia salmonis and infectious salmon anemia virus are required to maintain a long-term protection in farmed salmonids // Frontiers in Immunology. - 2015. - Vol. 6. Article 244.</mixed-citation><mixed-citation xml:lang="en">Tobar I., Arancibia S.,Torres C., Vera V., Soto P., Carrasco C., Alvarado M., Neira E., Arcos S.,Tobar J.A. Successive oral immunizations against Piscirickettsia salmonis and infectious salmon anemia virus are required to maintain a long-term protection in farmed salmonids // Frontiers in Immunology. - 2015. - Vol. 6. Article 244.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
